Reaxys is a platform independent, web-based product, so doesn’t require any installation efforts, but Java version 1.5 or higher has to be present on the system as a prerequisite.

Customers can access the product at www.reaxys.com. Platform independency means that it runs on Windows and Apple operating systems, so it can also be used on Macintosh computers. We support Internet Explorer (6 or higher), Firefox (2 or higher) and Safari (2 or higher). Technical requirements are available in the about section.

On www.info.reaxys.com you can receive information about the product, provide feedback and sign up for a newsletter designed to keep users and potential customers up to date regarding Reaxys. Especially important:

- ABOUT: benefits, accessibility, technical requirements
- SUPPORT:

• FAQ Frequently Asked Questions
• WEBINAR training schedule
  DOWNLOAD user guides and plug-ins (structure editor software)

- CONFERENCES: events where to see Reaxys
- CONTACT: e-customer care addresses (send your queries via email)

Reaxys support for Shibboleth is planned for Q2, 2010. There are no plans to support ATHENS.

This aspect is covered in the requirements, but requires further technical discussions with customers in order to be implemented.

Security is one of our biggest concerns and therefore Reaxys is accessible using HTTPS protocol. This requires port 443 to be open in a company’s firewall. Since this is a standard setting, it should not be a problem, unless the company prohibits all internet access.

Elsevier is committed to serving the needs of customers. Therefore, the customer is at the heart of all that we do. As Reaxys evolves, we will work closely with customers to develop new content and functionalities that support the way that they work. We are keen to be a partner for our customers in the synthesis design planning process and help them achieve their scientific goals.

Our Development Partners are a direct link to customers and end users in industry, academia and government institutions. They provide Reaxys with ideas and feedback on usability and functionality. The Development Partners contribute by thoroughly testing the interface for usability and product features, as well as providing ideas for future development.

Among the current development partners are:

• Boehringer Ingelheim
• Fujitsu
• Informationszentrum Chemie Biologie Pharmazie ETH Zürich
• Mercachem
• Novasep
• University of Bath
• Vienna University of Technology
•  Plus thirteen more partners

The RAB provides us with strategic guidance for the development of  Reaxys and ensure that we can tap into the necessary chemistry expertise to guide the products. Their roles include advising us on content coverage and functionality and, in general, representing the needs and views of the chemistry community at large. We are delighted that the Board includes so many eminent chemists including Nobel Laureates Bob Grubbs and Barry Sharpless.

Members of the Reaxys Advisory Board include:

• Dr. James E. Audia, Eli Lilly, Indianapolis, IN, USA
• Prof. A.G.M. Barrett, Imperial College, London, UK
• Prof. Dr. Erick M. Carreira, ETH Zürich, Switzerland
• Prof. Robert H. Grubbs, California Institute of Technology, Pasadena, CA, USA
• Dr. Torsten Hoffmann, F. Hoffmann-La Roche Ltd., Basel, Switzerland
• Prof. Dr. Horst Kunz, University of Mainz, Germany
• Dr. Ge Li, WuXi PharmaTech, Shanghai, China
• Dr. Graeme Robertson, Siena Biotech, Siena, Italy
• Dr. K. Barry Sharpless, Scripps Research Institute, La Jolla, CA, USA
• Prof. Barry M. Trost, Stanford University, CA, Stanford, CA, USA
• Prof. Henry N. C. Wong, The Chinese University of Hong Kong, China

Yes. Reaxys provides links to Scopus for all matching articles.

Visit the Reaxys website www.info.reaxys.com regularly for updates. You will also find a contact form to sign up for the newsletter, background about the team behind Reaxys, information about forthcoming conferences and events where you can have a demo of Reaxys.

Reaxys differs from CrossFire Commander in:

1. Presentation of content. Reaxys is based on the combined content of CrossFire Beilstein, Gmelin and the Patent Chemistry Database (PCD). The data are standardized and harmonized. Substance (reaction) data from all three sources are merged into one substance (reaction) record.

2. Interface. The Commander interface was mainly functionality driven (e.g. sort, group), highly-sophisticared, but not really easy to use. The Reaxys interface is task-driven (e.g. define a reaction query, get reaction results, refine on reaction properties and output into PDF), intuitive to use and provides a streamlined look and feel, making searches easier.

3. Functionality. We have been careful to ensure that all the key functionality that our users value in Commander are carried through to Reaxys, but made much easier to use and more visible. In addition we have taken the opportunity to add improved search, analysis and workflow tools that are designed around the needs of users. These include:

• Synthesis planner
• Additional search capabilities (e.g. generate structure query from name)
• Intelligent hit ranking and filtering tools
• Smart results visualization (e.g. tabular display)
• Web-application: no client installation on user PC
• Support of Apple Macintosh and OpenURL

We have been careful to bring across all of the key functionality valued by core CrossFire Commander users. Our focus is on serving the needs of research chemists and we have prioritized the inclusion of content and functionality that supports this group. We are continuously developing the interface and will provide more functionality with every release.

Yes, in many cases. However, a web environment is always different from a client-server system, which could affect results display times.

To the contrary – Reaxys includes more and different features without losing any of the previous functionality.

At www.info.reaxys.com (SUPPORT-> WEBINARS) you can find the current training schedule providing regular one hour webinars on specific topics. Seminars are held in English. Specific webinars can also be organized on request.

Under SUPPORT -> DOWNLOADS you can find the Reaxys Quick Reference Guide.

Yes - use CONTACT on www.info.reaxys.com to ask for a free trial.

Reaxys supports the following structure editors:

- Marvin Sketch (ChemAxon) - default structure editor
- ISIS/Draw (Symyx)
- Symyx Draw (Symyx)
- CrossFire Structure Editor (Elsevier)

Please note: if you wish to use other structure editors than Marvin Sketch, a plug-in has to be installed. This can be downloaded from http://www.info.reaxys.com/support_downloads.

Please refer to Reaxys' help system for more information on this topic.

Elsevier has matched the Reaxys compounds with two databases containing information about commercial availability: eMolecules and Symyx ACD (Available Chemicals Directory). In case of a successful match, icons are displayed by the compound within the Reaxys interface and a click on such an icon leads to the corresponding service.

Please note: access to ACD data is provided through Symyx' DiscoveryGate and requires a valid license to this service. Please contact Symyx for more details about ACD on DiscoveryGate.

Yes. The full text-link in Reaxys gives direct access to the publisher home pages including ScienceDirect (world's largest electronic collection of science, technology and medicine full-text and bibliographic information - owned by Elsevier) and EspaceNet (European Patent Office) and US Patent Office. Access to ScienceDirect and other literature publisher requires a subscription license. EspaceNet and USPTO are publicly available. 

We offer CWA-licenses (Corporate/Campus Wide Access) on a yearly subscription base including user authentication via IP-recognition - so no credentials needed here.

Reaxys has this functionality. To allow the user to change the application settings, save queries and search history and set up alerts, s/he can set his/her own username/password by using REGISTER in Reaxys. After login queries can be loaded and saved locally on the workstation and results can be saved.

Reaxys does not feature AutoNom and has no plans to do so. This is because tools which can generate an IUPAC name for a given structure are typically available in the structure editors with which Reaxys is compatible with (such as ChemDraw and Symyx Draw). The standard structure editor MarvinSketch from ChemAxon within Reaxys also contains this feature and is accessible through the menu item Tools -> Naming.

Please note: AutoNom is a 3rd party tool owned by the Beilstein Institute.