Reaxys differs from CrossFire Commander in:

1. Presentation of content. Reaxys is based on the combined content of CrossFire Beilstein, Gmelin and the Patent Chemistry Database (PCD). The data are standardized and harmonized. Substance (reaction) data from all three sources are merged into one substance (reaction) record.

2. Interface. The Commander interface was mainly functionality driven (e.g. sort, group), highly-sophisticared, but not really easy to use. The Reaxys interface is task-driven (e.g. define a reaction query, get reaction results, refine on reaction properties and output into PDF), intuitive to use and provides a streamlined look and feel, making searches easier.

3. Functionality. We have been careful to ensure that all the key functionality that our users value in Commander are carried through to Reaxys, but made much easier to use and more visible. In addition we have taken the opportunity to add improved search, analysis and workflow tools that are designed around the needs of users. These include:

• Synthesis planner
• Additional search capabilities (e.g. generate structure query from name)
• Intelligent hit ranking and filtering tools
• Smart results visualization (e.g. tabular display)
• Web-application: no client installation on user PC
• Support of Apple Macintosh and OpenURL